Treatment of filarial lymphoedema and elephantiasis with 5,6-benzo-α-pyrone (coumarin)
Identifieur interne : 00D014 ( Main/Exploration ); précédent : 00D013; suivant : 00D015Treatment of filarial lymphoedema and elephantiasis with 5,6-benzo-α-pyrone (coumarin)
Auteurs : J. R. Casley-Smith [Australie] ; C. T. Wang ; J. R. Casley-Smith [Australie] ; CUI ZI-HAISource :
- BMJ. British medical journal : (International ed.) [ 0959-8146 ] ; 1993.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Homme.
English descriptors
- KwdEn :
Abstract
Objective-To study efficacy of treatment of filarial lymphoedema and elephantiasis with 5,6-benzo-α-pyrone. Design-Randomised, double blind, placebo controlled study with matching for grade and duration of disease, age, and sex. Treatment was given for 367 days, and subjects were followed up for another year. Setting-A town in Shandong Province, China. Subjects-104 men and women with chronic unilateral filarial lymphoedema or elephantiasis of the leg: 64 were randomised to benzopyrone and 40 to placebo. By the end of the study 19 patients had dropped out of the treatment group and two out of the placebo group
Affiliations:
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Le document en format XML
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Chemotherapy</term>
<term>Coumarin</term>
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<term>Elephantiasis</term>
<term>Filariosis</term>
<term>Human</term>
<term>Lymphedema</term>
<term>Treatment</term>
<term>Treatment efficiency</term>
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<keywords scheme="Pascal" xml:lang="fr"><term>Traitement</term>
<term>Homme</term>
<term>Chimiothérapie</term>
<term>Filariose</term>
<term>Eléphantiasis</term>
<term>Efficacité traitement</term>
<term>Coumarine</term>
<term>Etude double insu</term>
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<front><div type="abstract" xml:lang="en">Objective-To study efficacy of treatment of filarial lymphoedema and elephantiasis with 5,6-benzo-α-pyrone. Design-Randomised, double blind, placebo controlled study with matching for grade and duration of disease, age, and sex. Treatment was given for 367 days, and subjects were followed up for another year. Setting-A town in Shandong Province, China. Subjects-104 men and women with chronic unilateral filarial lymphoedema or elephantiasis of the leg: 64 were randomised to benzopyrone and 40 to placebo. By the end of the study 19 patients had dropped out of the treatment group and two out of the placebo group</div>
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